Air pollution is a risk factor for diabetes, says study

Exposure to air pollution at the place of residence increases the risk of developing insulin resistance as a pre-diabetic state of type 2 diabetes.

Scientists of Helmholtz Zentrum München, in collaboration with colleagues of the German Center for Diabetes Research (DZD), reported these results in the journal Diabetes.

“Whether the disease becomes manifest and when this occurs is not only due to lifestyle or genetic factors, but also due to traffic-related air pollution,” said Professor Annette Peters, head of the research area of epidemiology of the DZD.

For the current study, she and her colleagues analyzed the data of nearly 3,000 participants of the KORA study who live in the city of Augsburg and two adjacent rural counties.

All individuals were interviewed and physically examined. Furthermore, the researchers took fasting blood samples, in which they determined various markers for insulin resistance and inflammation.

In addition, leptin was examined as adipokine which has been suggested to be associated with insulin resistance.

Non-diabetic individuals underwent an oral glucose tolerance test to detect whether their glucose metabolism was impaired.

The researchers compared these data with the concentrations of air pollutants at the place of residence of the participants.

They estimated air pollution using predictive models based on repeated measurements at 20 sites (for particle measurements) and at 40 sites (for nitrogen dioxide measurements) in the city and in the rural counties.

“The results revealed that people who already have an impaired glucose metabolism, so-called pre-diabetic individuals, are particularly vulnerable to the effects of air pollution,” said Dr. Kathrin Wolf, lead author of the study.

“In these individuals, the association between increases in their blood marker levels and increases in air pollutant concentrations is particularly significant!”

“Thus, over the long term — especially for people with impaired glucose metabolism — air pollution is a risk factor for type 2 diabetes.”

Next, the scientists want to investigate the influence of ultrafine particles.

“Diabetes will be a main focus of our research, also in this context. A precise knowledge of the risk factors is crucial for counteracting the increasing incidence of diabetes,” said Peters, looking to the future.

Source: Air pollution is a risk factor for diabetes, says study | Knowridge Science Report

About Respro® UK Ltd

Respro® Masks: Cycle masks, motorcycle masks and allergy masks. External wear for internal protection.
This entry was posted in Air Quality, Health Effects of Air Pollution and tagged , , , . Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s