Air pollution linked to increased rheumatoid arthritis severity

Air pollution is associated with increased rheumatoid arthritis (RA) disease severity, according to a study published in the October issue of Rheumatology.

Giovanni Adami, M.D., Ph.D., from the University of Verona in Italy, and colleagues collected longitudinal data of patients affected by RA and the daily concentrations of air pollutants in the Verona area to examine the correlation between RA flares and air pollution in a case-crossover study. Exposure to pollutants was compared in the 30- and 60-day periods preceding an arthritic flare relative to the 30- and 60-day exposure preceding a low-disease activity visit.

Data were included for 888 RA patients with 3,396 follow-up visits. The researchers identified an exposure-response relationship between air pollutant concentration and the risk for having abnormal C-reactive protein (CRP) levels. The risk for having CRP levels ≥5 mg/L were increased for patients exposed to higher concentrations of air pollutants. In the 60-day period preceding a flare, concentrations of carbon monoxide, nitric oxide, nitrogen dioxide, oxides of nitrogen, particulate matter with a diameter of 2.5 µm or less, and ozone were higher.

“The excessive risk was seen even at very low levels of exposure, even below the proposed threshold for the protection of human health,” the authors write. “Our study has important and direct consequences. In order to reduce the burden of RA, public and environmental health policy makers should aim to diminish gaseous and particulate matter emissions to a larger extent than currently recommended.”

Air pollution linked to increased rheumatoid arthritis severity

About Respro® UK Ltd

Respro® Masks: Cycle masks, motorcycle masks and allergy masks. External wear for internal protection.
This entry was posted in Air Quality, Health Effects of Air Pollution, Medical Studies and tagged , , . Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s